There’s minimal or no role for the administration of loop diuretics early in the management of APE. The majority of patients aren’t volume overloaded. Immediate care should focus on NIPPV and administration of nitroglycerin. In patients with ESRD, dialysis is what’s ultimately going to fix the patient.
High-dose NTG boluses in the treatment of sympathetic crashing acute pulmonary edema (SCAPE)