The risk of tendinopathy is increased in patients taking fluoroquinolones (FQs) along with steroids. Watch out for this combination in COPD patients.
FQs should be used cautiously in patients with risk factors associated with tendinitis, such as advanced age, history of tendon rupture, corticosteroid use, and/or acute or chronic renal dysfunction. Tendinitis can be misdiagnosed as a gouty flare, infection, or venous thrombosis (leg region involvement). Since Achilles tendinitis can be debilitating and
may lead to rupture, clinicians may need to monitor changes in gait and for symptoms suggestive of tendinopathy in patients on FQ therapy.